Cimetidine 400 mg tablet b.i.d. â†' liquid 300 mg/5 mL. Volume per dose?
6.7 mL is the volume per dose of liquid Cimetidine needed for a 400 mg tablet b.i.d.
To convert the prescribed 400 mg of Cimetidine into the corresponding liquid volume, we use the concentration of the liquid formulation, which is 300 mg per 5 mL. This calculation shows that each dose requires 6.7 mL of the liquid.
This volume is significantly lower than needed for the 400 mg dose. To achieve the required medication amount, one would need to calculate the volume based on the concentration, which is not supported by this choice.
This is the correct calculation. Given that the liquid formulation contains 300 mg per 5 mL, we can set up a proportion: (5 mL / 300 mg) = (x mL / 400 mg). Solving for x gives us 6.7 mL, which matches the required dosage for the patient.
This volume exceeds the calculated requirement for the 400 mg dose. If one were to use this volume, it would result in administering more medication than prescribed, potentially causing an overdose.
This option represents an even larger volume than choice C and would yield an excessive dosage of Cimetidine. There is no pharmacological basis for requiring this much liquid for a 400 mg dose, which should be accurately determined to avoid risks associated with overmedication.
When converting the prescribed dose of Cimetidine from a tablet to its liquid form, precise calculations based on concentration are crucial. The correct volume per dose is 6.7 mL, which ensures the patient receives the appropriate amount of medication. Incorrect choices either underestimate or overestimate the necessary volume, potentially leading to ineffective treatment or harmful side effects. Accurate dosing is essential for safe and effective medication administration.
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