Amoxicillin suspension is available in 250 mg/5 mL concentration. If a prescription calls for 375 mg t.i.d., what volume, in mL, is used daily?
22.5 mL is the total volume used daily for a 375 mg dose of amoxicillin suspension.
To determine the daily volume required for a 375 mg dosage, we first calculate the volume needed for each dose and then multiply by the number of doses (t.i.d. indicates three times a day). Given the concentration of 250 mg per 5 mL, we find that 375 mg corresponds to 7.5 mL, leading to a total daily volume of 22.5 mL.
This choice represents the volume needed for a single dose of 375 mg, calculated from the 250 mg/5 mL concentration. While accurate for one dose, it does not account for the total daily volume when administered three times a day.
The volume of 20 mL does not align with the required dosage calculations. At a concentration of 250 mg per 5 mL, 20 mL would equate to 1,000 mg, which far exceeds the prescribed daily total of 1,125 mg (375 mg x 3 doses).
This is the correct choice, as it accurately reflects the total daily volume of 22.5 mL needed for the medication, derived from administering 7.5 mL three times a day (7.5 mL x 3 = 22.5 mL).
A volume of 30 mL would correspond to a dosage of 1,500 mg per day, calculated from the concentration provided. This is significantly higher than the prescribed amount of 1,125 mg, making it incorrect.
To summarize, the calculation of 22.5 mL as the total daily volume of amoxicillin suspension aligns with the prescribed 375 mg three times a day. Each choice was evaluated based on the concentration provided, and only option C accurately reflected the required dosage, while the others were either too low or too high for the prescribed treatment.
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