According to USP Chapter 795, personal protective equipment (PPE) should be used to prevent:

Drug diversion refers to the illegal transfer of prescription medications from legal sources to illicit channels. While PPE helps maintain security in handling drugs, it does not directly address or prevent the issue of diversion, which is more related to regulatory control and monitoring rather than physical protection during drug preparation.

Therapeutic substitution involves replacing a prescribed medication with a different drug that is therapeutically equivalent. This practice is typically governed by policy and clinical guidelines and is unrelated to the use of PPE. PPE focuses on safety and contamination, not on medication management decisions.

Therapeutic adherence refers to a patient’s compliance with prescribed treatments. While PPE is important for ensuring safety during drug handling, it does not influence a patient's adherence to their medication regimen. Adherence is more closely linked to patient education and support rather than protective equipment.