Which of the following pairs is included on the list of look-alike/sound-alike medications maintained by the Institute for Safe Medication Practices (ISMP)?

Rationale

Rabeprazole and aripiprazole are included on the list of look-alike/sound-alike medications maintained by the Institute for Safe Medication Practices (ISMP).

The ISMP monitors and identifies medications that can cause confusion due to their similar names or appearances, which can lead to medication errors. Rabeprazole and aripiprazole are recognized for their phonetic and visual similarities, making them a notable pair on this list.

A (Rabeprazole and aripiprazole) CORRECT

This pair is included on the ISMP list because both names are similar in sound and appearance, which may lead to confusion during prescribing or dispensing. Rabeprazole is a proton pump inhibitor used to treat gastroesophageal reflux disease, while aripiprazole is an antipsychotic medication, and their similar endings can easily lead to mix-ups.

B (Prednisolone and risperidone) YOUR ANSWER

While both medications are important in their respective therapeutic areas—prednisolone being a corticosteroid and risperidone an antipsychotic—their names do not share the same level of phonetic or visual similarities as those in option A. Thus, they are not listed as look-alike/sound-alike medications by ISMP.

C (Nicardipine and naloxone) YOUR ANSWER

Nicardipine is a calcium channel blocker used for hypertension, while naloxone is an opioid antagonist. Although they may both be involved in critical care, their names do not exhibit the same phonetic resemblance that warrants inclusion on the ISMP list, distinguishing them from the correct answer.

D (Amlodipine and alprazolam) YOUR ANSWER

Amlodipine is also a calcium channel blocker, and alprazolam is a benzodiazepine. Despite some similarities, the differences in their prefixes and syllable structure make them less likely to be confused than the medications in option A, leading to their exclusion from the ISMP list.

Conclusion

The ISMP's list of look-alike/sound-alike medications aims to reduce the risk of medication errors by highlighting pairs that are easily confused. Rabeprazole and aripiprazole are included due to their similar phonetic and visual characteristics, whereas the other options do not exhibit the same level of risk, thereby reinforcing the importance of accurate medication identification in clinical practice.

Which of the following pairs is included on the list of look-alike/sound-alike medications maintained by the Institute for Safe Medication Practices (ISMP)?

Rabeprazole and aripiprazole are included on the list of look-alike/sound-alike medications maintained by the Institute for Safe Medication Practices (ISMP).

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