Difficulty: Easy
Average Score: 100%
"The trade in the market of Lisbon is a very considerable one because of the connection Lisbon has with all the other European markets and with the New World. The volume of the commercial exchanges is enormous, and the traders are very wealthy; they make huge amounts of money, lost by the Venetians, merely with the spices and drugs that are brought to Lisbon since the trade of Syria and Alexandria through the Red Sea expired around 1504." Report of two Venetian ambassadors accompanying King Philip II of Spain to Lisbon, Portugal, circa 1581-83

Which of the following most directly led to the changed status of Lisbon in the spice trade as described by the ambassadors?

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