Mammalian catalase will break down hydrogen peroxide into water and oxygen. One milliliter (mL) of catalase is added to a beaker containing 200 mL of hydrogen peroxide. Which of the following scenarios would cause an increase in the rate of the reaction?

Noncompetitive inhibitors bind to the enzyme regardless of whether the substrate is present, reducing the overall number of active enzyme molecules available for the reaction. This would decrease the reaction rate, as the enzyme's ability to catalyze the breakdown of hydrogen peroxide is impaired.

Competitive inhibitors compete with the substrate for binding to the active site of the enzyme. While they may temporarily reduce the reaction rate, their effect can be overcome by increasing substrate concentration. However, this still results in no net increase in the reaction rate compared to the scenario without the inhibitor.

Adding ice cubes would lower the temperature of the reaction mixture, decreasing molecular motion and the frequency of collisions between the catalase and hydrogen peroxide. This would result in a slower reaction rate, contrary to what is needed for an increase in the rate of reaction.