According to USP Chapter 800, gowns worn during the preparation of hazardous nonsterile compounds must:

This choice contradicts the fundamental safety principles outlined in USP Chapter 800. Gowns must be designed to prevent hazardous drugs from reaching the skin, so seams or closures that permit drug exposure would be unsafe and unacceptable for handling hazardous materials.

While gowns may need to be durable, the focus of USP Chapter 800 is on preventing contamination and exposure. Gowns should ideally be disposable or made from materials that are not porous and do not absorb hazardous residues, as absorption could lead to contamination and increased risk of exposure.

This option suggests designs that would actually increase the risk of exposure rather than minimize it. Gowns should have long sleeves and closed cuffs to ensure that hazardous drugs are contained and do not come into contact with the skin or clothing, thus providing maximum protection during compounding procedures.