According to USP Chapter 800, a reusable counting tray used to count out hazardous drugs, such as mercaptopurine tablets, must be:

Disposing of the counting tray after each use would be impractical and environmentally unsound, given that reusable trays are designed for multiple uses. This choice does not align with the guidelines promoting safe handling and sustainable practices in the management of hazardous drugs.

The term "activated" does not apply to counting trays in the context of hazardous drug handling. USP Chapter 800 does not mention any activation process for counting trays prior to use, as their purpose is to provide a clean and safe surface for counting rather than requiring an activation step.

While sterilization is crucial in certain contexts, it is not specifically required for counting trays under USP Chapter 800. The focus is on decontamination to remove hazardous drug residues rather than achieving complete sterility, which is typically more relevant for surgical instruments or settings involving aseptic techniques.