A pharmacy receives an order for mesalamine CR 1000 mg q.i.d. How many 250 mg capsules would be required for a 24-hour period?

Rationale

16 capsules of 250 mg are required for a 24-hour period.

To determine the total number of 250 mg capsules needed for a daily dosage of mesalamine CR 1000 mg taken four times a day (q.i.d.), we first calculate the total daily dose and then convert it into the number of capsules.

A (4) YOUR ANSWER

This option suggests that only 4 capsules are needed for the entire 24-hour period. However, with a prescribed total of 1000 mg per dose and four doses a day, this would only account for one dose, which is insufficient to meet the daily requirement.

B (12) YOUR ANSWER

Choosing 12 capsules implies a total daily dose of 3000 mg (12 capsules x 250 mg), which exceeds the prescribed total of 4000 mg (1000 mg x 4 doses). This calculation does not align with the required dosage, making it an incorrect choice.

C (16) CORRECT

This is the correct answer because 1000 mg per dose, taken four times a day, totals 4000 mg needed in 24 hours. Since each capsule contains 250 mg, dividing 4000 mg by 250 mg yields 16 capsules (4000 mg ÷ 250 mg = 16). This meets the exact requirement for the prescribed dosage.

D (25) YOUR ANSWER

Selecting 25 capsules would result in a total daily dosage of 6250 mg (25 capsules x 250 mg), which significantly exceeds the required 4000 mg for the 24-hour period. This option is therefore incorrect as it does not fulfill the specified medication order.

Conclusion

To fulfill an order of mesalamine CR 1000 mg q.i.d., the calculation shows that 16 capsules of 250 mg are needed to achieve the total daily dosage of 4000 mg. The other options miscalculate the amount needed, either by underestimating or overestimating the required dosage, making option C the only valid choice.

A pharmacy receives an order for mesalamine CR 1000 mg q.i.d. How many 250 mg capsules would be required for a 24-hour period?

16 capsules of 250 mg are required for a 24-hour period.

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